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Figure 4 | BMC Cancer

Figure 4

From: Small molecule receptor tyrosine kinase inhibitor of platelet-derived growth factor signaling (SU9518) modifies radiation response in fibroblasts and endothelial cells

Figure 4

PDGF-isoform dependent fibroblast proliferation assay. Fibroblasts were stimulated by PDGF-isoforms (-AA, -BB and -AB) at 2 ng/ml or 10 ng/ml for 72 hours after 1 hour pre-treatment with or without SU9518. SU9518 inhibited all three isoforms stimulated proliferation of fibroblasts (p < 0.05). The extent of inhibition was greater for PDGF-AB and -BB. Bars are means of 5 experiments ± SD.

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