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Table 1 PDK1-induced gene expression by qrt-PCR

From: 3-Phosphoinositide-dependent Protein Kinase-1 (PDK1) promotes invasion and activation of matrix metalloproteinases

Cell line WDNM1 TIMP3 Lck Collagen VI
Comma/vector 144.9 ± 11.0 156.5 ± 6.0 0.005 ± 0.001 0.56 ± 0.02
Comma/PDK1 3.1 ± 0.1 84.6 ± 2.3 43.6 ± 1.3 4.4 ± 0.3
-fold change -46.7 -1.8 8,720 7.9
-fold change in microarray -26.1 -2.4 41.1 10.0
  1. Values are expressed as the absolute mRNA levels present in Comma/PDK1 and Comma/vector cells in arbitrary units relative to the expression of β-actin. Each result is the mean ± S.E. of 3 determinations. The relative values from gene microarray analysis are shown for comparison