Table 4 Toxicity per cycle and per patient
Toxicity | Per cycle (n = 169) | Per patient (n = 33) | ||||
|---|---|---|---|---|---|---|
Hematological | Grade 2 | Grade 3 | Grade 4 | Grade 2 | Grade 3 | Grade 4 |
No. (%) | No. (%) | No. (%) | No. (%) | No. (%) | No. (%) | |
Leucopenia | 51 (30) | 31 (18) | 9 (5) | 11 (33) | 6 (18) | 8 (24) |
Neutropenia | 11 (6) | 22 (13) | 60 (36) | 2 (6) | 5 (15) | 18 (54) |
Thrombocytopenia | 12 (7) | 4 (2) | 0 | 5 (15) | 4 (12) | 0 |
Anemia | 26 (15) | 5 (3) | 0 | 12 (36) | 2 (6) | 0 |
Non hematological | ||||||
No. (%) | No. (%) | No. (%) | No. (%) | No. (%) | No. (%) | |
Nausea/vomiting | 14 (9) | 2 (1) | 0 | 9 (27) | 1 (3) | 0 (0) |
Diarrhea | 8 (5) | 1 (1) | 1 (1) | 7 (21) | 1 (3) | 1 (3) |
Stomatitis | 14 (8) | 1 (1) | 0 | 7 (21) | 1 (3) | 0 |
Neurosensory | 14 (8) | 0 | 0 | 6 (18) | 0 | 0 |
Fever | 16 (9) | 0 | 0 | 8 (24) | 0 | 0 |
Infection | 2 (1) | 0 | 0 | 1 (3) | 0 | 0 |
Thromboembolism | 2 (1) | 0 | 0 | 2 (6) | 0 | 0 |
Hypersensitivity | 1 (1) | 0 | 0 | 1 (3) | 0 | 0 |