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Table 2 Effect of ceramides on lymphoma and breast carcinoma cell lines apoptosis

From: CD40L induces multidrug resistance to apoptosis in breast carcinoma and lymphoma cells through caspase independent and dependent pathways

Culture conditions % of apoptotic cell: Mean (SE)
   LNH breast carcinoma
Drug L cells CD40L Daudi Raji BJAB BL36 BL70 T47 D BT20
- - 2 (0.3) 2 (0.3) 2 (0.3) 1 (0.2) 6 (0.5) 0 (0) 6 (0.5)
C2 - 24 (0.9) 64 (1) 13 (0.7) 64 (1) 67 (1) 29 (1) 13 (0.7)
C2 + 10 (0.7)a 17 (0.8)a 4 (0.4)a 42 (1)a 17 (0.8)a 8 (0.6)a 5 (0.5)a
C6 - 80 (0.9) 82 (0.9) 43 (1.1) 85 (0.8) 45 (1.1) 55 (1.1) 20 (0.9)
C6 + 59 (1.1)a 68 (1)a 12 (0.7)a 48 (1.1)a 20 (0.9)a 46 (1.1) 3 (0.4)a
C(-) - 3 (0.4) 7 (0.57) 1 (0.2) 1 (0.2) 4 (0.4) 2 (0.3) 3 (0.3)
  1. a: P < 0.05 (student's paired t-test) as compared with culture with ceramide alone