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Table 1 Multidrug resistance induced by CD40L in lymphoma cell lines

From: CD40L induces multidrug resistance to apoptosis in breast carcinoma and lymphoma cells through caspase independent and dependent pathways

Culture conditions % of apoptotic cell Mean (SE)
  LNH
Drug L cells CD40L DAUDI Raji BJAB BL36 BL70
- - 2 (0.3) 2 (0.3) 2 (0.3) 1 (0.2) 6 (0.5)
ETO - 46 (1.1) 16 (0.8) 29 (1) 45 (1.1) 23 (0.9)
ETO + 27 (1)a 17 (0.8) 17 (0.8)a 14 (0.77)a 7 (0.6)a
CDDP - 48 (1.1) 21 (0.9) 32 (1) 62 (1) 78 (0.9)
CDDP + 27 (1)a 9 (0.6)a 16 (0.8)a 25 (1)a 51 (1.1)a
DOX - 29 (1) 15 (0.8) 14 (0.8) 26 (1) 49 (1.1)
DOX + 16 (0.8)a 8 (0.6)a 6 (0.5)a 7 (0.6)a 13 (0.7)a
VIN - 50 (1.1) 32 (1) 28 (1) 55 (1.1) 33 (1)
VIN + 40 (1.1)a 17 (0.8)a 7 (0.6)a 46 (1.1)a 20 (0.9)a
TAX - 37 (1.1) 16 (0.8) 20 (0.9) 32 (1) 27 (1)
TAX + 16 (0.8)a 21 (0.9) 8 (0.6)a 17 (0.8)a 15 (0.8)a
  1. a: P < 0.05 (student's paired t-test) as compared to cells cultured with drug alone