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Figure 3 | BMC Cancer

Figure 3

From: CD40L induces multidrug resistance to apoptosis in breast carcinoma and lymphoma cells through caspase independent and dependent pathways

Figure 3

Modulation of PARP cleavage by drugs and CD40L expressing L cells in NHL and BCC carcinoma cell lines. BJAB cells (Panel A) and T47 D (Panel B) were incubated alone or with irradiated (75 Gy) L cells expressing CD40L then incubated with DOX (0.5 μg/ml), ETO (7.5 μg/ml), CDDP (7.5 μg/ml), VIN (50 nM) and TAX (50 nM) for 24 hours and finally washed and cultured without drugs with or without irradiated L cells expressing CD40L during 24 additional hours. Western blot were performed on 50 μg of total cell protein with PARP antibody. Data are representative of 3 experiments.

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