Table 2 Ki67, Mcm-2, a-Casp3, and Bcl-2 scores in the near (<1 mm from tumor) and far (>5 mm from tumor) areas of the normal and HGPIN compartments. Bold numerals indicate P value < 0.05 for difference between near and far glands.

Ki67 (% positive)

Luminal

1.25 (0.98,1.52)

1.18 (0.88,1.48)

10.77 (10.05,11.50)

6.43 (5.48,7.38)

Basal

6.47 (5.72,7.23)

6.29 (5.41,7.16)

6.12 (4.82, 7.41)

6.85 (5.02,8.68)

Total

3.27 (2.94,3.61)

3.09 (2.71,3.47)

10.04 (9.40,10.69)

6.52 (5.68,7.37)

Lum:Basal Ratio

0.19 (0.15,0.25)

0.19 (0.14,0.25)

1.76 (1.41, 2.20)

0.94 (0.69,1.27)

Mcm-2 (%positive)

Luminal

2.17 (1.78,2.56)

1.61 (1.26,1.95)

14.75 (13.84,15.67)

7.66 (6.74,8.59)

Basal

22.45 (21.33,23.56)

22.80 (21.46,24.15)

12.91 (11.10,14.72)

16.93 (14.80,19.07)

Total

12.24 (11.62,12.86)

10.62 (9.98,11.27)

14.41 (13.59,15.23)

10.20 (9.30,11.10)

Lum:Basal Ratio

0.10 (0.08,0.12)

0.07 (0.06,0.09)

1.14 (0.98,1.33)

0.45 (0.38,0.54)

a-casp3^a

1.72 (1.57,1.52)

1.52 (1.38,1.66)

0.60 (0.46,0.74)

0.88 (0.67,1.08)

Bcl-2^a

0.11 (0.04,0.19)

0.13 (0.05,0.22)

0.19 (0.07,0.31)

0.05 (0.00,0.11)