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Table 3 Significantly overrepresented GO categories from the Panther annotation database using the same gene set as Table 1.

From: Cross-platform expression profiling demonstrates that SV40 small tumor antigen activates Notch, Hedgehog, and Wnt signaling in human cells

Biological Process Observed Genes Expected Genes p-value
Cell structure and motility 175 118 3.6E-07
Cell communication 207 150 3.4E-06
Protein glycosylation 41 19 4.1E-06
Signal transduction 512 424 4.5E-06
Cell adhesion 107 68 5.6E-06
Carbohydrate metabolism 96 60 9.6E-06
Immunity and defense 220 166 2.5E-05
Protein modification 164 120 6.4E-05
Cell proliferation and differentiation 127 89 8.1E-05
Cell cycle 141 101 8.3E-05
Oncogenesis 101 69 1.6E-04
Cell structure 106 73 1.6E-04
Protein metabolism and modification 381 319 1.9E-04
Cell cycle control 75 49 2.3E-04
Developmental processes 304 249 2.4E-04
Extracellular matrix protein-mediated signaling 17 6 2.7E-04
Intracellular signaling cascade 138 103 4.1E-04
Tumor suppressor 26 13 0.001
Other polysaccharide metabolism 27 14 0.001
Apoptosis 81 57 0.001
Other metabolism 90 65 0.002
Receptor protein tyrosine kinase signaling pathway 36 21 0.002
Skeletal development 26 14 0.002
NF-kappaB cascade 18 8 0.003
Cell motility 52 35 0.003
Nucleoside, nucleotide and nucleic acid metabolism 441 390 0.004
Cell adhesion-mediated signaling 52 35 0.004
Mesoderm development 83 62 0.005
DNA replication 20 11 0.007
DNA metabolism 53 37 0.007
Lipid, fatty acid and steroid metabolism 105 82 0.008
Stress response 35 22 0.008