Table 1 Characteristics of neurological toxicity during or after first-line chemotherapy with carboplatin plus paclitaxel
Neurological toxicity | No. of patients | % |
|---|---|---|
A. during chemotherapy (n = 120) | Â | Â |
   No toxicity | 55 | (46%) |
   At least grade 1 toxicity | 65 | (54%) |
Type of toxicity | Â | Â |
Sensory, grade 1 | 51 | (42%) |
Sensory, grade 2 | 13 | (11%) |
Sensory, grade 3 | 1 | (1%) |
Motor, grade 1 (combined with sensory) | 3 | (3%) |
B. residual toxicity after chemotherapy (n = 60 - 5 patients lost) | Â | Â |
   No toxicity at the moment of interview | 46 | (77%) |
Time to recovery from residual neuropathy | Â | Â |
< 2 months after the end of chemotherapy | 22 | 37% |
≥ 2 < 6 months after the end of chemotherapy | 15 | 25% |
≥ 6 months after the end of chemotherapy | 9 | 15% |
   At least grade 1 residual toxicity at the moment of interview | 14 | (23%) |
Type of residual toxicity | Â | Â |
Sensory, grade 1 | 12 | (20%) |
Sensory, grade 2 | 2 | (3%) |
Motor, grade 1 (combined with sensory) | 3 | (5%) |