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Table 6 Dose of interferon received and actual dose intensity.

From: Tolerability of intensified intravenous interferon alfa-2b versus the ECOG 1684 schedule as adjuvant therapy for stage III melanoma: a randomized phase III Italian Melanoma Inter-group trial (IMI – Mel.A.) [ISRCTN75125874]

  DD/DI arm (N = 86) HDI arm (N = 80)
  Mean (SD) Median (Range) Mean (SD) Median (Range)
Target dose (MU/m2) 1600   1840  
MU/m2 received 974.6 (455.6) 1034.4 (40 -1620.2) 1052.2 (509.2) 1155.9 (20-1888.9)
Target DI* MU/m2/week 50   35.4  
Actual DI MU/m2/week 37.1 (10.8) 36.4 (5–52.1) 34.1 (14.4) 30.7 (5–91.8)
% of target DI 0.74 (0.2) 0.73 (0.1–1.0) 0.96 (0.4) 0.87 (0.1–2.6)
  1. *DI: Dose Intensity
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