From: Tolerability of intensified intravenous interferon alfa-2b versus the ECOG 1684 schedule as adjuvant therapy for stage III melanoma: a randomized phase III Italian Melanoma Inter-group trial (IMI – Mel.A.) [ISRCTN75125874]
Number of cycles (%)
DD/DI arm
HDI arm
N° cycles delivered
272
701
According to protocol
72
(26)
187
(27)
Modified in dose less than 20%
64
(23)
176
(25)
Modified in dose more than 20%
136
(50)
338
(48)