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Table 2 Acute and late toxicity after radiotherapy and chemotherapy according to RTOG/ECOG and LENT scores (highest level given)

From: A non-randomised, single-centre comparison of induction chemotherapy followed by radiochemotherapy versus concomitant chemotherapy with hyperfractionated radiotherapy in inoperable head and neck carcinomas

 

SEQ

  

CON

   
 

Grade III

Grade IV

Grade III

Grade IV

p

 

n

(%)

n

(%)

n

(%)

N

(%)

 

Acute toxicity (RTOG)

       

Skin

11

(16)

0

 

5

(10)

0

 

n.s.

Mucositis

31

(44)

1

(1)

28

(54)

2

(4)

n.s.

Pharynx

9

(13)

1

(1)

9

(17)

1

(2)

n.s.

Salivary glands

10

(14)

0

 

4

(8)

0

 

n.s.

Late toxicity (LENT scores)

       

Skin

2

(3)

0

 

2

(4)

0

 

n.s.

Subcutis

5

(7)

0

 

7

(14)

0

 

n.s.

Mucosa

4

(6)

0

 

3

(6)

0

 

n.s.

Salivary glands

7

(10)

0

 

3

(6)

0

 

n.s.

Pharynx

5

(7)

0

 

4

(8)

1

(2)

n.s.

Larynx

3

(4)

0

 

2

(4)

0

 

n.s.

Mandibula

1

(1)

0

 

0

 

1

(2)

n.s.