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Table 3 Summary of correlation of immunohistochemical abnormalities with clinicopathologic characteristics in ESCC

From: Tissue microarray analysis reveals a tight correlation between protein expression pattern and progression of esophageal squamous cell carcinoma

  

Sex

Age

Differentiation

Protein

 

Male

Female

P

60

<60

P

well

moderate

poor

P

 

-

92

20

 

53

59

 

16

56

40

 

Fas

+

55

10

0.053

33

32

0.088

23

29

13

0.002

 

++

8

6

 

11

3

 

7

5

2

 
 

-

80

15

 

46

49

 

26

47

22

 

FADD

+

59

20

0.278

40

39

0.781

21

33

25

0.043

 

++

19

4

 

13

10

 

0

15

8

 
 

-

49

14

 

38

25

 

17

29

17

 

CDC25B

+

89

18

0.480

47

60

0.103

25

49

33

0.852

 

++

20

7

 

15

12

 

5

15

7

 
 

-

23

11

 

21

13

 

6

12

16

 

Fascin

+

66

12

0.114

37

41

0.347

18

35

25

0.028

 

++

68

16

 

41

43

 

23

46

15

 
 

-

59

16

 

38

37

 

6

27

42

 

CK14

+

35

4

0.241

20

19

0.977

11

21

7

<0.001

 

++

64

19

 

41

42

 

31

44

8

 
 

-

90

16

 

50

56

 

17

53

36

 

CK4

+

66

20

0.242

49

37

0.018

27

39

20

0.056

 

++

4

2

 

0

6

 

3

2

1

 
 

-

92

0

 

49

63

 

22

51

39

 

Annexin 1

+

52

14

0.843

41

25

0.059

21

30

12

0.085

 

++

15

4

 

9

10

 

5

12

5

 
 

-

39

15

 

26

28

 

11

16

27

 

Laminin-5γ2

+

90

18

0.191

59

49

0.425

32

57

19

<0.001

 

++

28

5

 

14

19

 

4

19

10

 
 

-

22

12

 

14

20

 

5

14

15

 

SPARC in stromal fibroblasts

+

48

12

0.031

26

34

0.079

11

27

22

0.004

 

++

74

12

 

51

35

 

28

45

13

 
 

-

146

38

 

97

87

 

44

88

52

 

SPARC in epithelial cells

+

5

1

0.397

1

5

0.108

1

3

2

0.866

 

++

7

0

 

2

5

 

2

2

3

Â