|  | Sex | Age | Differentiation | |||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Protein | Â | Male | Female | P | 60 | <60 | P | well | moderate | poor | P |
 | - | 92 | 20 |  | 53 | 59 |  | 16 | 56 | 40 |  |
Fas | + | 55 | 10 | 0.053 | 33 | 32 | 0.088 | 23 | 29 | 13 | 0.002 |
 | ++ | 8 | 6 |  | 11 | 3 |  | 7 | 5 | 2 |  |
 | - | 80 | 15 |  | 46 | 49 |  | 26 | 47 | 22 |  |
FADD | + | 59 | 20 | 0.278 | 40 | 39 | 0.781 | 21 | 33 | 25 | 0.043 |
 | ++ | 19 | 4 |  | 13 | 10 |  | 0 | 15 | 8 |  |
 | - | 49 | 14 |  | 38 | 25 |  | 17 | 29 | 17 |  |
CDC25B | + | 89 | 18 | 0.480 | 47 | 60 | 0.103 | 25 | 49 | 33 | 0.852 |
 | ++ | 20 | 7 |  | 15 | 12 |  | 5 | 15 | 7 |  |
 | - | 23 | 11 |  | 21 | 13 |  | 6 | 12 | 16 |  |
Fascin | + | 66 | 12 | 0.114 | 37 | 41 | 0.347 | 18 | 35 | 25 | 0.028 |
 | ++ | 68 | 16 |  | 41 | 43 |  | 23 | 46 | 15 |  |
 | - | 59 | 16 |  | 38 | 37 |  | 6 | 27 | 42 |  |
CK14 | + | 35 | 4 | 0.241 | 20 | 19 | 0.977 | 11 | 21 | 7 | <0.001 |
 | ++ | 64 | 19 |  | 41 | 42 |  | 31 | 44 | 8 |  |
 | - | 90 | 16 |  | 50 | 56 |  | 17 | 53 | 36 |  |
CK4 | + | 66 | 20 | 0.242 | 49 | 37 | 0.018 | 27 | 39 | 20 | 0.056 |
 | ++ | 4 | 2 |  | 0 | 6 |  | 3 | 2 | 1 |  |
 | - | 92 | 0 |  | 49 | 63 |  | 22 | 51 | 39 |  |
Annexin 1 | + | 52 | 14 | 0.843 | 41 | 25 | 0.059 | 21 | 30 | 12 | 0.085 |
 | ++ | 15 | 4 |  | 9 | 10 |  | 5 | 12 | 5 |  |
 | - | 39 | 15 |  | 26 | 28 |  | 11 | 16 | 27 |  |
Laminin-5γ2 | + | 90 | 18 | 0.191 | 59 | 49 | 0.425 | 32 | 57 | 19 | <0.001 |
 | ++ | 28 | 5 |  | 14 | 19 |  | 4 | 19 | 10 |  |
 | - | 22 | 12 |  | 14 | 20 |  | 5 | 14 | 15 |  |
SPARC in stromal fibroblasts | + | 48 | 12 | 0.031 | 26 | 34 | 0.079 | 11 | 27 | 22 | 0.004 |
 | ++ | 74 | 12 |  | 51 | 35 |  | 28 | 45 | 13 |  |
 | - | 146 | 38 |  | 97 | 87 |  | 44 | 88 | 52 |  |
SPARC in epithelial cells | + | 5 | 1 | 0.397 | 1 | 5 | 0.108 | 1 | 3 | 2 | 0.866 |
 | ++ | 7 | 0 |  | 2 | 5 |  | 2 | 2 | 3 |  |