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Figure 3 | BMC Cancer

Figure 3

From: High resolution melting analysis for the rapid and sensitive detection of mutations in clinical samples: KRAS codon 12 and 13 mutations in non-small cell lung cancer

Figure 3

Sensitivity of the KRAS HRM assay for different amplicons. Panel A: The HCT116 dilutions were compared to the median wild-type control sample to produce the difference plot for the 189 bp amplicon. Panel B: The HCT116 dilutions were compared to the median wild-type control sample to produce the difference plot for the 92 bp amplicon. Panel C: The A549 dilutions were compared to the median wild-type control sample to produce the difference plot for the 189 bp amplicon. Panel D: The A549 dilutions were compared to the median wild-type control sample to produce the difference plot for the 92 bp amplicon. Panel E: The RPMI8226 dilutions were compared to the median wild-type control sample to produce the difference plot for the 189 bp amplicon. Panel F: The RPMI8226 dilutions were compared to the median wild-type control sample to produce the difference plot for the 92 bp amplicon.

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BMC Cancer

ISSN: 1471-2407

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