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Table 3 Cox multivariate regression analysis: TNM tumour staging (stage I vs stages I, II, III, IV).

From: Prognostic significance of multidrug-resistance protein (MDR-1) in renal clear cell carcinomas: A five year follow-up analysis

Co-variables

Significance (p)

Sex

0,613

Age*

0,715

Death from disease

0,004

Grading*

0,993

Tumour Size*

0,939

Multicentric Pattern of Growth

0,181

Thrombosis of caval vein

0,075

Necrosis

0,72

Adjuvant Therapy

0,783

  1. We have considered tumour stage as state variable in correlation with different clinical and histopathological co-variables. The only significant statistical association has been observed between tumour stage and unfavourable outcome (p = 0.004).
  2. *: for these co-variables, we have fixed the different cut-off values (≤ 65 years vs > 65 years for Age, G1 vs G2–G3–G4 for Grading, 7 cm vs > 7 cm as regards Tumour Size).