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Table 1 Characteristics of selected genes in this study

From: Etiological study of esophageal squamous cell carcinoma in an endemic region: a population-based case control study in Huaian, China

Loci Gene location Genotypes Restriction enzymes Methods References
CYP1A1 3'-flanking 6235 T to C MspI PCR-RFLP Hong et al, 1998 [25]
CYP1A1 exon 7 Ile462Val NocI PCR-RFLP London et al, 2000 [27]
CYP1B1 exon 3 Val432Leu Eco57I PCR-RFLP Saintot et al, 2004 [28]
CYP2A6 exon7–9 Deletion - Two step-PCR Tan et al, 2001 [30]
CYP2E1 5'-flanking c1/c2 RsaI PCR-RFLP Tan et al, 2000 [22]
GSTM1 Whole gene GSTM1(-) 1 No amplification Multiplex PCR Wang et al, 2003 [23]
GSTT1 Whole gene GSTT1(-) 1 No amplification Multiplex PCR Wang et al, 2003 [23]
GSTP1 exon 5 Ile105Val Alw26I PCR-RFLP Harries et al, 1997 [26]
EHPX 113 exon 3 Tyr113His Tth111I PCR-RFLP de Jong et al, 2003 [29]
EPHX 139 exon 4 His139Arg RsaI PCR-RFLP de Jong et al, 2003 [29]
  1. 1null genotype.