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Table 4 Comparison of accelerated or hyperfractionated radiotherapy with conventionally fractionated radiotherapy (Group 2/3)

From: A meta-analysis of hyperfractionated and accelerated radiotherapy and combined chemotherapy and radiotherapy regimens in unresected locally advanced squamous cell carcinoma of the head and neck

   control arm experimental arm   
publication trial # dose [Gy] RT time [days] dose [Gy] RT time [days] fractionation Stage 4 [%] N3 [%]
group 2   conventional fract. acceleration   
Dische [16] 20 66 45.5 54 12 CHART 72 6
Dobrowsky [37] 21 70 49.0 55.3 17 CHART   12
Olmi [41] 22 68 47.3 65.6 42.7 AF split 70 7
Fu [42] 23 70 49.0 67.2 43.4 AF split 68 13
v. den Bogaert [43] 24 72.5 56.0 69.6 44.8 AF split 65 47
Horiot [23] 25 70 51.7 72 35 AF split 0 0
Fu [42] 26 70 49.0 72 42 concomittant boost   
Overgaard [44] 27 66–68 39.0 66–68 46.0 weekend 25  
Skladowsky [13] 28 70.6 54 70.75 40 weekend 17 0
group 3   conventional fract. hyperfractionation   
Sanchiz [18] 29 60 42.0 70.4 44.8 HFX   30
Pinto [45] 30 66 46.2 70.4 44.8 HFX 54 25
Horiot [46] 31 70 51.1 80.5 49 HFX   15
Fu [42] 32 70 49.0 81.6 47.6 HFX 68 13