Figure 5From: Gefitinib (IRESSA) sensitive lung cancer cell lines show phosphorylation of Akt without ligand stimulationSummary of expression of Her2 and phosphorylation of EGFR in 23 lung cancer cell lines grown under serum-containing (cross bars) and serum-free (black bars) conditions. (A) the ratio of phosphorylated EGFR signal/EGFR signal; (B) the ratio of Her2 signal/β-actin signal. The density of expression of each of the molecules was measured by NIH Image. Point: mean of three independent experiment; bars, ± standard deviation (SD). The expression ratio of the molecules in serum-free conditions was compared between gefitinib-resistant and gefitinib-sensitive cell lines using the Mann-Whitney test; point, mean, bars, ± standard error (SE). *P < 0.05 was considered to be statistically significant.Back to article page