Figure 3From: Gefitinib (IRESSA) sensitive lung cancer cell lines show phosphorylation of Akt without ligand stimulationSummary of expression of PTEN and phosphorylation of Akt in 23 lung cancer cell lines grown under serum-containing (cross bars) and serum-free (black bars) conditions. (A) The ratio of phosphorylated Akt signal/total Akt signal (pAkt/Akt); (B) the ratio of PTEN signal/β-actin signal; The density of expression of each of the molecules was measured by NIH Image. Point: mean of three independent experiment; bars, ± standard deviation (SD). The expression ratio of the molecules in serum-free conditions was compared between gefitinib-resistant and gefitinib-sensitive cell lines using the Mann-Whitney test; point, mean, bars, ± standard error (SE). *P < 0.05 was considered to be statistically significant.Back to article page