Table 12 Significant biological functions for MIN-O vs PL expression differences for 8w-D line

Response to radiation/UV

   phototransduction

GO:0007602

0.00E+00

   detection of light

GO:0009583

0.00E+00

   response to radiation

GO:0009314

0.00E+00

   response to light

GO:0009416

0.00E+00

   response to UV

GO:0009411

2.88E-02

Apoptosis

   apoptotic program

GO:0008632

0.00E+00

Immune response

   complement activation, classical pathway

GO:0006958

9.56E-03

   positive regulation of immune response

GO:0050778

1.15E-02

   regulation of immune response

GO:0050776

1.36E-02

   T-cell activation

GO:0042110

2.23E-02

   antigen processing

GO:0030333

2.25E-02

   cellular defense response (sensu Vertebrata)

GO:0016066

2.32E-02

   antimicrobial humoral response

GO:0019730

2.58E-02

   positive regulation of lymphocyte activation

GO:0051251

2.60E-02

   xenobiotic metabolism

GO:0006805

2.58E-02

   symbiotic interaction between host and other organism

GO:0044404

2.56E-02

   oxygen and reactive oxygen species metabolism

GO:0006800

3.21E-02

   complement activation

GO:0006956

3.21E-02

   response to xenobiotic stimulus

GO:0009410

3.97E-02

   lymphocyte differentiation

GO:0030098

3.94E-02

   pathogenesis

GO:0009405

3.96E-02

   T-helper 1 type immune response

GO:0042088

4.19E-02

   detection of biotic stimulus

GO:0009595

4.49E-02

   cytokine and chemokine mediated signaling pathway

GO:0019221

4.72E-02

   antigen presentation, endogenous antigen

GO:0019883

4.71E-02

   lymphocyte proliferation

GO:0046651

4.90E-02

   antigen presentation

GO:0019882

8.19E-03

Angiogenesis

   blood vessel morphogenesis

GO:0048514

8.92E-03

   blood vessel development

GO:0001568

1.17E-02

   angiogenesis

GO:0001525

1.47E-02

ECM

   extracellular structure organization and biogenesis

GO:0043062

3.18E-02

   extracellular matrix organization and biogenesis

GO:0030198

3.15E-02

   cell-matrix adhesion

GO:0007160

4.31E-02

Signaling pathways

   I-kappaB kinase/NF-kappaB cascade

GO:0007249

0.00E+00

   regulation of I-kappaB kinase/NF-kappaB cascade

GO:0043122

2.38E-02

   positive regulation of I-kappaB kinase/NF-kappaB cascade

GO:0043123

2.35E-02

   Wnt receptor signaling pathway

GO:0016055

1.16E-04

   Ras protein signal transduction

GO:0007265

4.61E-03

   inactivation of MAPK

GO:0000188

2.43E-02

Steroid

   steroid biosynthesis

GO:0006694

3.27E-06

   sterol metabolism

GO:0016125

4.16E-02