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Table 12 Significant biological functions for MIN-O vs PL expression differences for 8w-D line

From: Heterogeneity of mammary lesions represent molecular differences

Name GO ID Corrected P-value
Response to radiation/UV   
   phototransduction GO:0007602 0.00E+00
   detection of light GO:0009583 0.00E+00
   response to radiation GO:0009314 0.00E+00
   response to light GO:0009416 0.00E+00
   response to UV GO:0009411 2.88E-02
Apoptosis   
   apoptotic program GO:0008632 0.00E+00
Immune response   
   complement activation, classical pathway GO:0006958 9.56E-03
   positive regulation of immune response GO:0050778 1.15E-02
   regulation of immune response GO:0050776 1.36E-02
   T-cell activation GO:0042110 2.23E-02
   antigen processing GO:0030333 2.25E-02
   cellular defense response (sensu Vertebrata) GO:0016066 2.32E-02
   antimicrobial humoral response GO:0019730 2.58E-02
   positive regulation of lymphocyte activation GO:0051251 2.60E-02
   xenobiotic metabolism GO:0006805 2.58E-02
   symbiotic interaction between host and other organism GO:0044404 2.56E-02
   oxygen and reactive oxygen species metabolism GO:0006800 3.21E-02
   complement activation GO:0006956 3.21E-02
   response to xenobiotic stimulus GO:0009410 3.97E-02
   lymphocyte differentiation GO:0030098 3.94E-02
   pathogenesis GO:0009405 3.96E-02
   T-helper 1 type immune response GO:0042088 4.19E-02
   detection of biotic stimulus GO:0009595 4.49E-02
   cytokine and chemokine mediated signaling pathway GO:0019221 4.72E-02
   antigen presentation, endogenous antigen GO:0019883 4.71E-02
   lymphocyte proliferation GO:0046651 4.90E-02
   antigen presentation GO:0019882 8.19E-03
Angiogenesis   
   blood vessel morphogenesis GO:0048514 8.92E-03
   blood vessel development GO:0001568 1.17E-02
   angiogenesis GO:0001525 1.47E-02
ECM   
   extracellular structure organization and biogenesis GO:0043062 3.18E-02
   extracellular matrix organization and biogenesis GO:0030198 3.15E-02
   cell-matrix adhesion GO:0007160 4.31E-02
Signaling pathways   
   I-kappaB kinase/NF-kappaB cascade GO:0007249 0.00E+00
   regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 2.38E-02
   positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 2.35E-02
   Wnt receptor signaling pathway GO:0016055 1.16E-04
   Ras protein signal transduction GO:0007265 4.61E-03
   inactivation of MAPK GO:0000188 2.43E-02
Steroid   
   steroid biosynthesis GO:0006694 3.27E-06
   sterol metabolism GO:0016125 4.16E-02