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Table 3 Quality of life mean score changes before and after 3 cycles of chemotherapy (follow-up scores minus baseline scores) for each study arms

From: Quality of life in patients with advanced gastric cancer: a randomized trial comparing docetaxel, cisplatin, 5-FU (TCF) with epirubicin, cisplatin, 5-FU (ECF)

  ECF group   TCF group  
Functioning scores 1 Mean (SD) score changes P3 Mean (SD) score changes P3
Physical functioning 4.1 (13.6) 0.08 2.3 (14.8) 0.36
Role functioning 0.57 (14.3) 0.81 2.7 (18.9) 0.38
Emotional functioning -0.06 (8.3) 0.96 8.0 (15.4) 0.004
Cognitive functioning -2.5 (13.4) 0.27 -6.1 (17.0) 0.04
Social functioning -2.3 (14.6) 0.36 5.2 (14.1) 0.03
Global quality of life 2.4 (14.5) 0.34 9.7 (16.8) 0.001
Symptom scores 2     
Fatigue -0.99 (14.8) 0.69 -4.6 (14.1) 0.05
Nausea and vomiting -3.5 (19.6) 0.29 -1.4 (29.9) 0.78
Pain -6.3 (14.2) 0.01 -5.7 (15.1) 0.03
Dyspnoea -2.6 (14.9) 0.31 -0.92 (20.3) 0.78
Sleep difficulties -5.8 (23.5) 0.15 -11.3 (27.5) 0.02
Appetite loss -4.6 (19.8) 0.17 -5.4 (29.3) 0.27
Constipation -1.1 (29.4) 0.83 0.92 (36.9) 0.88
Diarrhoea 9.8 (19.0) 0.004 0.32 (27.6) 0.94
Financial difficulties 9.1 (23.6) 0.03 11.6 (19.3) 0.001
  1. 1 For functioning scores positive values show improvements and negative values indicate deteriorations.
  2. 2 For symptom scores negative values show improvements and positive values indicate deteriorations.
  3. 3 P values derived from the paired t-tests.
  4. SD = Standard deviation