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Table 2 Distribution of C677T and A1298C genotypes by race/ethnicity1

From: Association of MTHFR gene polymorphisms with breast cancer survival

  African-American n (%) Caucasian n (%) p-value2 Combined n (%)
C677T     
   C/C 114 (81) 49 (48) < 0.001 163 (67)
   C/T 27 (19) 44 (43)   71 (29)
   T/T 0 9 (9)   9 (4)
A1298C     
   A/A 98 (69) 37 (36) < 0.001 135 (56)
   A/C 38 (27) 49 (48)   87 (36)
   C/C 5 (4) 16 (16)   21 (8)
  1. 1 Only cases who were successfully genotyped for both SNPs (n = 243) are included
  2. 2 Chi-square test comparing genotype distributions between African-Americans and Caucasians