Maspin HSCORE versus tumor parameters. Box-and-whisker plots of Maspin HSCORE above/below cutpoint and tumor dimension (A), of Maspin HSCORE versus depth of tumor invasion (B), and Maspin HSCORE versus vascular invasion (C). The open squares represent those outlier patients outside the 95% confidence interval. The black solid circles represent the mean values, while the line inside the box represents the median. (D) Bar-chart plot of patients with Maspin HSCORE above/below cutpoint versus vascular invasion.