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Table 1 Clinico-pathological and genetic data of 41 neuroblastic tumors.

From: Frequent promoter hypermethylation of RASSF1A and CASP8 in neuroblastoma

Tumor Age Sex Localization Diagnosis Shimada Histology Ki 67 LOH 1p MYCN amp.
1 3 y M Mediastinum GN n.a. 1% n.a. n.a.
17 13 y M Mediastinum GN Stroma rich. Dif. Low MKI. 1% n.a. n.a.
94 4 y M Suprarenal GN Stroma rich. Dif. Low MKI. 15% n.a. n.a.
3 5 y M Suprarenal GNB Stroma rich. Dif. Low MKI. 5% n.a. n.a.
5 3 y F Suprarenal GNB Stroma rich. Nodular 5% NO NO
7 3 y F Retroperitoneum GNB Stroma rich. Mixed 2% NO NO
8 1 y F Suprarenal GNB Stroma rich. Nodular n.a. NO YES (10 copies)
9 7 y M n.a. GNB Stroma rich. Dif. Low MKI. 10% NO NO
10 4 y M Retroperitoneum GNB Stroma rich. Dif. Mild MKI. 15% YES NO
61 1 y F Mediastinum GNB Stroma rich. Dif. Low MKI. 10% n.a. NO
82 2 y M Retroperitoneum GNB Stroma rich. Nodular n.a. NO NO
83 6 y V Mediastinum GNB Stroma rich. Nodular 15% NO NO
86 2 y F Retroperitoneum GNB Stroma rich. Dif. Low MKI. 15% n.a. YES (10–50 copies)
92 6 y M Mediastinum GNB Stroma rich. Nodular 15% NO NO
107 1 y M Thoracic-abdominal GNB Stroma rich. Mixed 5% YES NO
12 2 m F Suprarenal NB Stroma poor. Undif. Mild MKI. 50% NO YES (20 copies)
13 11 m M Abdominal NB Stroma poor. Undif. High MKI. 60% NO NO
14 2 y M Retroperitoneum NB Stroma poor. Dif. Low MKI. 40–50% YES YES (50 copies)
15 3 y M Suprarenal NB Stroma poor. Dif. Mild MKI. 40–50% NO NO
16 9 y M Mediastinum NB Stroma poor. Undif. High MKI. 60% NO NO
18 6 y F Thoracic-abdominal NB Stroma poor. Undif. Mild MKI. 60% YES NO
33 9 y M Suprarenal NB Stroma poor. Undif. High MKI. 70% NO NO
37 2 w F Retroperitoneum NB Stroma Poor. Undif. Low MKI. 10% NO NO
34 2 m F Mediastinum NB Stroma poor. Dif. 15% YES NO
45 3 w F Suprarenal NB Stroma poor. Undif. Low MKI. 10% YES NO
48 7 m F Paraaortic NB Stroma rich. Dif Low MKI. 5% n.a. NO
51 4 w M Suprarenal NB Stroma poor. Dif. 20% NO NO
52 1 m F Suprarenal NB Stroma poor. Undif. Low MKI. 10% n.a. NO
63 5 m M Suprarenal NB Stroma poor. Undif. 40% NO NO
64 2 y M Suprarenal NB Stroma poor. Undif. n.a. n.a. NO
73 2 y F Suprar. retroper NB Stroma poor. Undif. 85% YES YES
77 4 y M Retroperitoneum NB Stroma poor. Undif. 25% NO NO
85 4 y M Suprarenal NB Stroma poor. Undif. Mild MKI. 30% n.a. NO
87 3 y M Hypochondrium NB Stroma poor. Undif. High MKI. 30% n.a. YES (10 copies)
90 12 y n.a. Brain NB n.a. n.a. n.a. n.a.
91 3 y F Retroperitoneum NB Stroma poor. Undif. 25% NO NO
95 4 m F Suprarenal NB Stroma poor. Undif. n.a. YES n.a.
96 3 y F n.a. NB Stroma poor. Undif. 50% n.a. n.a.
97 4 m F Suprarenal NB Stroma poor. Undif. 10% NO n.a.
99 2 m F Thoracic-abdominal NB Stroma poor. Undif. High MKI. 60% n.a. n.a.
102 1 y F Mediastinum NB Stroma poor. Undif. Low MKI. 15% YES NO
  1. F: female. M: man. y: year/years. M: month/months. w: weeks. GN: Ganglioneuroma. GNB: Ganglioneuroblastoma. NB: Neuroblastoma. Dif: differentiated. Undif: undiferentiated. MKI: mitosis-karyorrhexis index. MYCN amp.: MYCN amplification. n.a.: data non avaible.
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