Figure 1
From: Frequent promoter hypermethylation of RASSF1A and CASP8 in neuroblastoma
Loss of heterozygosity study at D3S3522 polymorphic marker in neuroblastic tumors. PCR products were run in a 15% polyacrylamide gel and visualized after ethidium bromide staining (0.5 μg/ml) T: DNA from tumor tissue; N: DNA from peripheral blood of the same patient; M1/M2: 10 bp DNA ladder/1 Kb Plus DNA ladder (Invitrogen™ Life and Technologies, Carlsbad, CA, USA). Sample number 64 showed microsatellite instability.