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Table 3 Gene data summary.

From: Microarray-based identification and RT-PCR test screening for epithelial-specific mRNAs in peripheral blood of patients with colon cancer

Gene symbol

Gene description

Function

Summary*

PRSS22

Protease, serine, 22 (Location: 16p13.3)

Serine-type endopeptidase activity

Member of the trypsin family of serine proteases. Enzyme expressed in the airways in a developmentally regulated manner. Serine proteases are involved in blood coagulation, growth factor processing, the digestion of nutrients, and cell migration. Northern hybridization showed that prosemin is expressed predominantly in the pancreas and weakly in the prostate and cerebellum.

RANBP3

RAN binding protein 3 (Location: 19p13.3)

Ran GTPase binding

The RAN GTPase plays an essential role in the transport of macromolecules between the cytoplasm and the nucleus, cell cycle progression, spindle assembly, nuclear organization and nuclear envelope (NE) assembly. RANBP3 (RAN binding protein 3) contains FXFG motifs characteristic of a subgroup of nucleoporins, and a C-terminal domain showing similarity to RANBP1.

TMEM69

Transmembrane protein 69 (Location: 17q21.2)

Unknown

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  1. *http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene