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Table 5 Correlation between the amplification and molecular breast subtypes.

From: Frequency, prognostic impact, and subtype association of 8p12, 8q24, 11q13, 12p13, 17q12, and 20q13 amplifications in breast cancers

Region of amplification Basal Non Basal p-value ERBB2 Non ERBB2 p-value Luminal A Non Luminal A p-value
  No. of patients (%)   No. of patients (%)   No. of patients (%)  
11q13          
Amplification 1 (5.5) 22 (45.8) p = 0.006 2 (25) 21 (36.2) NS 19 (57.6) 4 (12.1) p = 0.0003
No Amplification 17 (94.5) 26 (54.2)   6 (75) 37 (63.8)   14 (42.4) 29 (87.9)  
12p13          
Amplification 5 (27.8) 2 (4.2) p = 0.02 1 (11.1) 6 (10.5) NS 1 (3.1) 6 (17.6) NS
No Amplification 13 (72.2) 46 (95.8)   8 (88.9) 51 (89.5)   31 (96.9) 28 (82.4)  
17q12          
Amplification 0 (0) 6 (17.6) NS 5 (71.4) 1 (2.2) p = 2.061e-06 0 (0) 6 (20) NS
No Amplification 19 (100) 28 (82.4)   2 (28.6) 45 (97.8)   23 (100) 24 (80) p = 0.065
  1. NS: Not significant