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Table 4 Multivariant analysis of the TMA study set

From: Prognostic significance of fascin expression in advanced colorectal cancer: an immunohistochemical study of colorectal adenomas and adenocarcinomas

a. Cox's proportional hazard analysis in stage I to IV patients

Variables

Risk ratio (95% confidence interval)

p

Age (≥65y)

1.618(0.944–2.774)

0.080

Gender (male)

0.615(0.365–1.036)

0.068

Lymph node metastasis (N1,2)

3.952(2.276–6.861)

<0.001*

Distant metastasis (M1)

1.720(0.938–3.155)

0.797

Tumor location (distal)

1.039(0.593–1.820)

0.894

Fascin (high)

1.184(0.905–3.676)

0.925

b. Cox's proportional hazard analysis in stage III and IV patients

Age (≥65y)

1.259(0.683–2.318)

0.460

Gender (male)

0.603(0.322–1.129)

0.114

Lymph node metastasis (N1,2)

0.969(0.336–2.791)

0.934

Distant metastasis (M1)

1.245(0.539–2.628)

0.566

Tumor location (distal)

1.464(0.776–2.765)

0.240

Fascin (high)

2.301(1.045–5.068)

0.039*