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Table 4 Multivariant analysis of the TMA study set

From: Prognostic significance of fascin expression in advanced colorectal cancer: an immunohistochemical study of colorectal adenomas and adenocarcinomas

a. Cox's proportional hazard analysis in stage I to IV patients
Variables Risk ratio (95% confidence interval) p
Age (≥65y) 1.618(0.944–2.774) 0.080
Gender (male) 0.615(0.365–1.036) 0.068
Lymph node metastasis (N1,2) 3.952(2.276–6.861) <0.001*
Distant metastasis (M1) 1.720(0.938–3.155) 0.797
Tumor location (distal) 1.039(0.593–1.820) 0.894
Fascin (high) 1.184(0.905–3.676) 0.925
b. Cox's proportional hazard analysis in stage III and IV patients
Age (≥65y) 1.259(0.683–2.318) 0.460
Gender (male) 0.603(0.322–1.129) 0.114
Lymph node metastasis (N1,2) 0.969(0.336–2.791) 0.934
Distant metastasis (M1) 1.245(0.539–2.628) 0.566
Tumor location (distal) 1.464(0.776–2.765) 0.240
Fascin (high) 2.301(1.045–5.068) 0.039*