Table 1 Odds Ratios and 95% confidence intervals (CI) for the development of cervical cancer in relation to -308 TNF-α alleles among the cervical cancer cases and controls in the two South African ethnic population groups.
Race | Genotype | CaCx n (%) | Controls n (%) | OR1 (95%CI) |
|---|---|---|---|---|
1. All # | Â | (n = 244) | (n = 228) | Â |
|  | GG | 174 (71) | 172 (76) | 1.29 (0.49 – 3.37) |
|  | AG | 62 (26) | 46 (20) | 1.80 (0.66 – 4.97) |
| Â | AA | 8 (3) | 10 (4) | 1 |
2. Mixed race | Â | (n = 83) | (n = 59) | Â |
|  | GG | 64 (77) | 45 (76) | 2.93 (0.51–16.72) |
|  | AG | 17 (21) | 10 (17) | 3.78 (0.58–24.75) |
| Â | AA | 2 (2) | 4 (7) | 1 |
3. Black | Â | (n = 161) | (n = 169) | Â |
|  | GG | 110 (68) | 127 (72) | 0.87 (0.27–2.76) |
|  | AG | 45 (28) | 36 (24) | 1.25 (0.37–4.21) |
| Â | AA | 6 (4) | 6 (4) | 1 |