Figure 1

Relationship between gene expression and clinical evolution of disease. The box plot shows the median, upper and lower quartiles and minimum and maximum values for related gene expression. A- Relative expression of THBS3 in groups of OS patients represented by samples obtained from the biopsy diagnosis (n = 16), primary tumor surgery (n = 19) and metastases (n = 17) ; B- Relative expression of SPARC in groups of OS patients represented by samples obtained from the biopsy diagnosis (n = 26), primary tumor surgery (n = 16) and metastases (n = 13); C- Relative expression of SPP1 in groups of OS patients represented by samples obtained from the biopsy diagnosis (n = 16), primary tumor surgery (n = 20) and metastases (n = 17).