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Figure 5 | BMC Cancer

Figure 5

From: Fusion of the BCL9 HD2 domain to E1A increases the cytopathic effect of an oncolytic adenovirus that targets colon cancer cells

Figure 5

The E1A-HD2 virus shows increased toxicity on cells with activated Wnt signaling. A. CPE assays. Cells were infected with 10-fold dilutions of virus starting from 100 pfu/cell in HeLa, Hct116 and HT29 cells, and starting from 10 pfu/cell in ISREC-O1 and SW480 cells. B. MTT assays in the same cell lines. Dotted line, parental virus. Solid line, E1A-HD2 virus. C. The change in EC50 calculated from the data in B.

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BMC Cancer

ISSN: 1471-2407

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