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Table 3 VEGF and IL-8 in relation to clinicopathological indicators and eIF4E reactivity

From: Eukaryotic Initiation Factor 4E (eIF4E) and angiogenesis: prognostic markers for breast cancer

Variable VEGF p value IL-8 p value
  (-) (1+) (2+) (3+)   (-) (1+) (2+) (3+)  
Total 29 38 34 21   21 40 37 24  
Age (median, 56 years)           
   <56 years 13 21 17 8 0.43 13 18 24 11 0.24
   ≥56 years 16 17 27 13   8 22 13 13  
Tumor size           
   <3.1 cm 20 20 15 7 0.09 15 20 14 10 0.08
   ≥3.1 cm 9 18 10 14   6 20 23   
Invasive carcinoma grade           
   Grade I 14 19 8 2 0.003 10 17 8 2 0.022
   Grade II 10 12 12 6   6 13 11 9  
   Grade III 5 7 14 13   5 10 18 13  
TNM staging           
   Stage I 10 14 7 1 0.007 9 13 6 3 0.048
   Stage II 9 10 9 3   6 14 10 4  
   Stage III 7 8 8 4   3 8 9 6  
   Stage IV 3 6 10 13   3 5 12 11  
eIF4E expression           
   Low reactivity 20 18 17 4 0.007 15 19 20 5 0.007
   High reactivity 9 20 17 17   6 21 17 19