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Table 2 Correlations of eIF4E with clinicopathological parameters

From: Eukaryotic Initiation Factor 4E (eIF4E) and angiogenesis: prognostic markers for breast cancer

  eIF4E expression
Variable n Low reactivity High reactivity p value
   n % n %  
Total 122 59 48.4 63 51.6  
Age (median, 56 years)       
   <56 years 68 31 25.4 37 30.3 0.49
   ≥ 56 years 54 28 23.0 26 21.3  
Tumor size       
   <3.1 cm 70 37 30.3 33 27.0 0.25
   ≥3.1 cm 52 22 18.1 30 24.6  
Histological diagnosis       
   Invasive carcinoma 102 45 36.9 57 46.7 0.034
   Non invasive carcinoma 20 14 11.5 6 4.9  
Invasive carcinoma type       
   Ductal 80 34 33.3 46 45.1 0.72
   Lobular 14 8 7.8 6 5.9  
   Medullary 6 2 2.0 4 3.9  
   Tubular 2 1 1.0 1 1.0  
Invasive carcinoma grade       
   Grade I 27 17 16.7 10 9.8 0.016
   Grade II 41 19 18.6 22 21.6  
   Grade III 34 9 8.8 25 24.5  
TNM staging       
   Stage I 30 16 13.1 14 11.5 0.54
   Stage II 33 18 14.8 15 12.3  
   Stage III 37 17 13.9 20 16.4  
   Stage IV 22 8 6.6 14 11.4  
Node metastatic status       
   Negative 48 20 16.4 28 22.9 0.23
   Positive 74 39 32.0 35 28.7  
ER status       
   Negative 54 24 19.7 30 24.6 0.44
   Positive 68 35 28.7 33 27.0  
PR status       
   Negative 65 29 23.8 36 29.5 0.38
   Positive 57 30 24.6 27 22.1  
Her-2/neu status       
   Negative 66 34 27.9 32 26.2 0.45
   Positive 56 25 20.5 31 25.4