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Table 2 Correlations of eIF4E with clinicopathological parameters

From: Eukaryotic Initiation Factor 4E (eIF4E) and angiogenesis: prognostic markers for breast cancer

 

eIF4E expression

Variable

n

Low reactivity

High reactivity

p value

  

n

%

n

%

 

Total

122

59

48.4

63

51.6

 

Age (median, 56 years)

      

   <56 years

68

31

25.4

37

30.3

0.49

   ≥ 56 years

54

28

23.0

26

21.3

 

Tumor size

      

   <3.1 cm

70

37

30.3

33

27.0

0.25

   ≥3.1 cm

52

22

18.1

30

24.6

 

Histological diagnosis

      

   Invasive carcinoma

102

45

36.9

57

46.7

0.034

   Non invasive carcinoma

20

14

11.5

6

4.9

 

Invasive carcinoma type

      

   Ductal

80

34

33.3

46

45.1

0.72

   Lobular

14

8

7.8

6

5.9

 

   Medullary

6

2

2.0

4

3.9

 

   Tubular

2

1

1.0

1

1.0

 

Invasive carcinoma grade

      

   Grade I

27

17

16.7

10

9.8

0.016

   Grade II

41

19

18.6

22

21.6

 

   Grade III

34

9

8.8

25

24.5

 

TNM staging

      

   Stage I

30

16

13.1

14

11.5

0.54

   Stage II

33

18

14.8

15

12.3

 

   Stage III

37

17

13.9

20

16.4

 

   Stage IV

22

8

6.6

14

11.4

 

Node metastatic status

      

   Negative

48

20

16.4

28

22.9

0.23

   Positive

74

39

32.0

35

28.7

 

ER status

      

   Negative

54

24

19.7

30

24.6

0.44

   Positive

68

35

28.7

33

27.0

 

PR status

      

   Negative

65

29

23.8

36

29.5

0.38

   Positive

57

30

24.6

27

22.1

 

Her-2/neu status

      

   Negative

66

34

27.9

32

26.2

0.45

   Positive

56

25

20.5

31

25.4

 
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