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Figure 5 | BMC Cancer

Figure 5

From: Identification of genes associated with cisplatin resistance in human oral squamous cell carcinoma cell line

Figure 5

Expression of CCND1 and CCND3 in primary oral squamous cell carcinoma. Fifty specimens of primary oral squamous cell carcinoma were collected and classified into resistant (red column) and sensitive (blue column) groups on the basis of growth inhibition as assessed by the modified MTT assay, 25 cases in each group. A. Immunstaining results were ranked according to the staining percentage: '-' (0–5%), '+'(5%-20%), '++' (20%-50%) and '+++' (>50%). B. Mann-Whitney U test showed that CCND1 (P = 0.021) and CCND3 (P = 0.013) were differentially expressed in primary tumors in a manner consistent with their drug resistance patterns.

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