Skip to main content

Table 3 Copy Number Aberrations associated with overall and progression-free survival.

From: Medulloblastoma outcome is adversely associated with overexpression of EEF1D, RPL30, and RPS20 on the long arm of chromosome 8

Copy Number Aberration

n

Overall Survival p value (log-rank)

Progression-Free Survival p value (log-rank)

2p gain (including amplifications)

12 (16)

0.5257 (0.0848)

0.3938 (0.0701)

8q gain (including amplifications*)

6 (7)

0.0005** (0.0141**)

< 0.0001** (0.0004**)

  1. * Multivariate analysis controlling for clinical variables (i.e. metastatic stage, degree of resection, and age relative to 3 years) revealed statistically significant differences in OS (p value, 0.013) and PFS (p value, 0.003).
  2. ** Statistically significant differences by log-rank testing.