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Table 3 The relation of poor clinical and pathological response to the clinico-pathological variables.

From: CA 15-3 is predictive of response and disease recurrence following treatment in locally advanced breast cancer

 

Poor clinical Response

p value

Poor pathological Response

p value

Tumour size

    

   <2.5 cm

1/29(3.4%)

 

5/45(11%)

 

   >2.5 cm

28/29(96.5%)

0.052

40/45(88.8%)

0.001

Tumour Histology

    

   Ductal

26/29(89.6%)

0.216

40/45(74%)

0.187

   Lobular

1/29(3.4%)

 

2/45(3.7%)

 

   Mixed

2/29(6.8%)

 

3/45(5.5%)

 

Tumour stage

    

   II

2/29(6.8%)

 

8/45(17.7%)

0.26

   III

24/29(82.7%)

0.014

37/45(82.2%)

0.26

   IV

3/29(10.3%)

 

Non

 

Her2/neu positive

8/29(27.5%)

0.410

8/45(17.7%)

0.666

ER positive

18/29(62.1%)

0.396

32/45(91.4)

0.052

LVI

13/29(44.8%)

0.141

23/45(51.1%)

0.034

CA 15-3 before PC

13/29(50%)

0.013

17/45(37.7%)

0.044

CA 15-3 after PC

14/29(46.2%)

0.012

16/45(35.5%)

0.045

  1. Fisher's exact test was used for categorical variables and Wilcoxon's test for continuous variables. A P-value of less than 0.05 was considered to be significant. LVI (lympho-vascular space invasion) and PC (primary chemotherapy).