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Table 3 Comparative gene expression levels from microarray and RT-PCR analysis

From: Increased therapeutic potential of an experimental anti-mitotic inhibitor SB715992 by genistein in PC-3 human prostate cancer cell line

Gene

Description

Microarray 48 h Fold Change

RT-PCR 48 h Fold Change

IL-11

interleukin 11

-4.59

-2.13

CDK11

cyclin-dependent kinase (CDC2-like) 11

128.00

4.03

FRK

fyn-related kinase

25.99

11.00

p15

cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)

9.19

5.41

CHD2

chromodomain helicase DNA binding protein 2

14.93

15.74

CNOT

CCR4-NOT transcription complex, subunit 3

-4.29

-5.01

p57

cyclin-dependent kinase inhibitor 1C (p57, Kip2)

6.06

35.84

ELF3

E74-like factor 3 (ets domain transcription factor)

6.96

24.53

ACVR

activin A receptor, type IIB

11.31

2.95

TNFSF

tumor necrosis factor (ligand) superfamily, member 15

11.31

30.00

EGFR

epidermal growth factor receptor

2.00

6.00

p27

cyclin-dependent kinase inhibitor 1B (p27, Kip1)

3.03

10.90

KRAS2

v-Ki-ras2 Kirsten rat sarcoma 2 viral oncogene homolog

19.7

3.56

FGF

fibroblast growth factor

-6.06

-5.26