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Table 3 Association of CpG island hypermethylation and clinico-pathological parameters in endometrial cancer.

From: Differential DNA methylation profiles in gynecological cancers and correlation with clinico-pathological data

 

All subjects

CDH13

APC

p16

hMLH1

Any loci

  

+

-

+

-

+

-

+

-

+

-

Case

60

25

35

21

39

15

45

8

52

40

20

Mean age (yrs)

58.2

59.2

57.5

58.4

58.1

59.3

57.9

62.2

57.6

59.3

56.0

   P value (T-test)

  

0.619

 

0.944

 

0.724

 

0.377

 

0.38

Stage

           

I

46

20

26

17

29

15

31

6

40

35

11

II-IV

14

5

9

4

10

0

14

2

12

5

9

   P value(χ2 test)

  

0.606

 

0.565

 

0.014

 

0.905

 

0.005

Grade

           

G1

35

12

23

10

25

11

24

1

34

22

13

G2–3

25

13

12

11

14

4

21

7

18

18

7

   P value(χ2 test)

  

0.17

 

0.217

 

0.174

 

0.007

 

0.459

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BMC Cancer

ISSN: 1471-2407

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