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Table 3 Association of CpG island hypermethylation and clinico-pathological parameters in endometrial cancer.

From: Differential DNA methylation profiles in gynecological cancers and correlation with clinico-pathological data

  All subjects CDH13 APC p16 hMLH1 Any loci
   + - + - + - + - + -
Case 60 25 35 21 39 15 45 8 52 40 20
Mean age (yrs) 58.2 59.2 57.5 58.4 58.1 59.3 57.9 62.2 57.6 59.3 56.0
   P value (T-test)    0.619   0.944   0.724   0.377   0.38
Stage            
I 46 20 26 17 29 15 31 6 40 35 11
II-IV 14 5 9 4 10 0 14 2 12 5 9
   P value(χ2 test)    0.606   0.565   0.014   0.905   0.005
Grade            
G1 35 12 23 10 25 11 24 1 34 22 13
G2–3 25 13 12 11 14 4 21 7 18 18 7
   P value(χ2 test)    0.17   0.217   0.174   0.007   0.459