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Figure 1 | BMC Cancer

Figure 1

From: Differential DNA methylation profiles in gynecological cancers and correlation with clinico-pathological data

Figure 1

Identification of CpG island hypermethylation by pooled DNA approach and MSP. Methylated alleles for some gene loci produced by MSP in tumor and normal DNA pools of the three types of gynecologic cancer. M: 50 bp DNA marker; M1 and M2: normal DNA and tumor DNA pools of cervical cancer; M3 and M4: normal DNA and tumor DNA pools of endometrial cancer; M5 and M6: normal DNA and tumor DNA pools of ovarian cancer; M7: a sodium bisulfite-treated placenta DNA, but without pre-treatment of SssI methyltransferase; M8: an un-treated placenta DNA; M9: a placenta DNA treated with SssI methyltransferase followed by sodium-bisulfite. The arrows indicate the positions of the PCR products.

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