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Table 3 Correlation between molecular biomarkers and histological grade in all breast cancer specimens.

From: Telomerase activity, estrogen receptors (α, β), Bcl-2 expression in human breast cancer and treatment response

Histological grade

Low Grade

Intermediate and High Grade

X 2

P value

 

n (%)

n (%)

  

Telomerase activity

    

Positive

8 (40)

18(75)

4.5

0.033*

Negative

12 (60)

6(25)

  

Bcl-2

    

Positive

10(83)

25(78)

0.14

0.7

Negative

2(17)

7(22)

  

ER alpha

    

Positive

12(100)

27(84)

2.11

0.15

Negative

0 (0)

5 (16)

  

ER beta

    

Positive

4(32)

12(37)

0.65

0.8

Negative

8(68)

20(63)

  
  1. *Fisher's exact test (two-tailed). p significance at ≤ 0.05.