Skip to main content

Advertisement

Table 2 Karyotype analysis of primary/recurrent tumor cells

From: Over-representation of specific regions of chromosome 22 in cells from human glioma correlate with resistance to 1,3-bis(2-chloroethyl)-1-nitrosourea

Clonal Designation Karyotypic deviation
DI 45,X,-X,+7,-10[9]/45,idem,-9,der(9)t(9;11)(p22;q21),-11[13]/45,idem,-9,der(9)t(9;11)(p22;q21),-11,-14,-18,del(11) (q21),der(14)t(14;18)(P11;q12),der(22)t(22:?)(p11;?)[44]/90,idem ×2[5]/88,idem ×2,+6,+11,-11,+15,15,+19 [cp12]/85-86,idem,+X,-3,+5,-8,+11,-11,+12,+12,-13,+15,-15,i(15q),-19,+20,-20,+21[31] non-clonal cells [1] 46,XX[13]
DIR 45,X,-X,+7,-9,-10,-11,-14,-18,der(9)t(9;11)(p22;q21),del(11)(q21),der(14)t(14;18)(P11;q12),der(22)t(22:?) (p11;?)[159] non-clonal cells[7]
ME 45,XX,del(9)(p13),add(9)(p21),+9-13,-17[9]/47,idem,+mar1,+mar2,1-3dmin[6]/48,idem,+7[8]/49,idem,+mar3[13]/90,idem×2[5]/80-85,idem×2,-1,+8,-8,-10,+11,-11,+12,-12,-19,-21,-21-22,+mar3,3-7dmin[cp38] non-clonal cells [9] 46,XX[6]
MER 55,X,der(X)t(X:?)(q25;?),der(1)t(1;?)((p32;?),×2,+1,inv(2)(p13q21),der(2)t(2;14)(q23;q13),add(2)(p25.1),+2,add(3) (q29) ×2,+3,-4,del(5)(q13),-5,iso(7)(p11.1),der(9)t(9;1)(p22;p13),del(10)(p11.2), der(10)t(10;?)(q22;?),inv(11)(q13q23)×2,+11,-12,-13,-15, -17,add(18)(q23),add(19)(q13.3), add(20)(q13.3),-22,+mar1,+mar2,+mar3,+mar4,+mar5[16]/56,idem, +7,[36]/57,+7,+mar6 [5] non-clonal cells [23]
LX 56-57,XX,+1,-1,+2,+2,+6,-6,i(6)(p10),+7,+7,+8,+9,der(9)t(9;12)(p13;q11),ins(9;?)(p13;?),+11,+14,+15,+16,-17,del(17)(p11.2),+21,-22,2-3mar[cp11]69,XX,+1,+3, add(3) (q29),x2,+3,+3,+4,del(5)(p13.3p15.1)del(6)q22)×2,+6,+7,+7,+7,del(9)(p13) ×2,+11,+11,+12,+15, +15,-17,-17,+18, +18,+20,+20,+21,+21,+mar3,+mar4,+mar5,[21]/68,idem,-10,-mar3,+mar5[19]/67,idem,-3, -10,+17,-mar3,+mar6[10] non-clonal cells [6]
LXR 46-49,XX, +1, -1, del(1)(p13), del(1)(q12), del(1)(q25), der(?)t(1;?)(q21;?),-2, -2, der(2)t(2;9)(p13;q13),der(2)ins(2;4)(q11.2;12q34), add(2)(q31), -3, add(3)(q21), del(3)(p22;p23),-4, der(4)t(4;8)(q13.2;q11.2), -5, del(5)(p15.1;p15.2), add(5)(q11.1), -6, der(6)t(1;6)(p11;q11), del(6)(q21), add(7)(q21.2), +der(7)t(7;?)(q11.2;?), -9, add(9)(q32), -10, +11, add(11)(p11.2), -12, add(12)(q24.3), -13, add(15)(q21.2), -16, del(17)(p11.2) ×2, add(20)(q11.1), -21, +22, 5, -6, mar[cp41] non-clonal (16)