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Table 7 Probable frequencies of the common haplotypes in the interleukin-1 gene cluster in breast cancer and screening control cohorts.

From: Interleukin gene polymorphisms and breast cancer: a case control study and systematic literature review

Haplotype* Frequency Case, Control Ratios Chi-square P value
GCCT 0.330 471.5 : 938.5, 321.5 : 674.5 0.352 0.5529
TTCT 0.165 220.7 : 1189.3, 176.8 : 819.2 1.865 0.1720
GCTC 0.133 182.1 : 1227.9, 138.3 : 857.7 0.469 0.4934
GCTT 0.112 169.0 : 1241.0, 99.9 : 896.1 2.239 0.1346
GCCC 0.099 145.8 : 1264.2, 91.3 : 904.7 0.913 0.3392
TCCT 0.032 42.1 : 1367.9, 35.4 : 960.6 0.602 0.4376
TCTT 0.026 32.4 : 1377.6, 30.1 : 965.9 1.202 0.2729
GTCT 0.024 36.1 : 1373.9, 22.6 : 973.4 0.214 0.6440
TTCC 0.022 33.5 : 1376.5, 19.9 : 976.1 0.377 0.5394
TTTT 0.017 21.2 : 1388.8, 19.8 : 976.2 0.817 0.3661
TCCC 0.016 24.6 : 1385.4, 14.1 : 981.9 0.4 0.5271
TCTC 0.013 16.7 : 1393.3, 14.3 : 981.7 0.295 0.5873
  1. * The haplotypes represent the four polymorphisms (IL1A +4845G>T, IL1B +3954C>T, IL1B -511C>T and IL1RN +2018T>C) in that order.