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Table 1 Relationship between the Bcl-2 protein expression and the clinicopathological factors in breast cancer.

From: Bcl-2 protein expression is associated with p27 and p53 protein expressions and MIB-1 counts in breast cancer

 

No. of patients

Bcl-2 protein expression (%)

  

normal

decreased

p value

Tumor size (cm)

   

0.0770

   - 2.0

57

37 (65)

20 (35)

 

   2.1 – 5.0

162

95 (59)

67 (41)

 

   5.1 -

30

12 (40)

18 (60)

 

Lymph node metastasis*

   

0.9507

   absent

137

79 (58)

58 (42)

 

   present

110

63 (57)

47 (43)

 

Nuclear grade

   

< 0.0001

   I or II

168

122 (73)

46 (27)

 

   III

81

22 (27)

59 (73)

 

Estrogen receptor (ER)

   

< 0.0001

   positive

109

90 (83)

19 (17)

 

   negative

140

54 (39)

86 (61)

 

p27 protein expression

   

< 0.0001

   normal

140

111 (79)

29 (21)

 

   decreased

109

33 (30)

76 (70)

 

p53 protein expression

   

< 0.0001

   negative

183

123 (67)

60 (33)

 

   positive

66

21 (32)

45 (68)

 

MIB-1 counts

   

< 0.0001

   negative (< 10%)

147

101 (69)

46 (31)

 

   positive (≥ 10%)

102

43 (42)

59 (58)

 
  1. * Lymph node dissection was performed in 247 patients