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Table 1 Relationship between the Bcl-2 protein expression and the clinicopathological factors in breast cancer.

From: Bcl-2 protein expression is associated with p27 and p53 protein expressions and MIB-1 counts in breast cancer

  No. of patients Bcl-2 protein expression (%)
   normal decreased p value
Tumor size (cm)     0.0770
   - 2.0 57 37 (65) 20 (35)  
   2.1 – 5.0 162 95 (59) 67 (41)  
   5.1 - 30 12 (40) 18 (60)  
Lymph node metastasis*     0.9507
   absent 137 79 (58) 58 (42)  
   present 110 63 (57) 47 (43)  
Nuclear grade     < 0.0001
   I or II 168 122 (73) 46 (27)  
   III 81 22 (27) 59 (73)  
Estrogen receptor (ER)     < 0.0001
   positive 109 90 (83) 19 (17)  
   negative 140 54 (39) 86 (61)  
p27 protein expression     < 0.0001
   normal 140 111 (79) 29 (21)  
   decreased 109 33 (30) 76 (70)  
p53 protein expression     < 0.0001
   negative 183 123 (67) 60 (33)  
   positive 66 21 (32) 45 (68)  
MIB-1 counts     < 0.0001
   negative (< 10%) 147 101 (69) 46 (31)  
   positive (≥ 10%) 102 43 (42) 59 (58)  
  1. * Lymph node dissection was performed in 247 patients