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Figure 3 | BMC Cancer

Figure 3

From: Inhibition of cyclooxygenase-2 decreases breast cancer cell motility, invasion and matrix metalloproteinase expression

Figure 3

The effect of COX-2 inhibition on the migration of MDA-231 cells. A) Cells (1 × 105) were placed in the upper chamber inserts with or without NS-398 in serum-free DMEM and allowed to migrate for 24 h. FCM was used as a chemoattractant to stimulate the migration of the cells. B) Wound migration assay. Confluent MDA-231 cells cultured in six well dishes were wounded with a sterile pipette tip and then incubated with or without Niflumic Acid for 24 h. Photographs were taken with a phase contrast microscope and measurements with Adobe photoshop 6.0. Values were significant (*p < 0.05, **p < 0.01) when compared to untreated controls (0 μM NA or NS-398).

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