Skip to main content

Table 2 Summary of IS-RT-PCR results obtained for expression of β-actin, MT1-MMP, MMP-1 and MMP-3 in HBC cell line derived xenograft tissues. The intensity is a value from zero to four (0+ to 4+) based on the overall level of signal intensity observed throughout the entire section.

From: In vitro and in vivo MMP gene expression localisation by In Situ-RT-PCR in cell culture and paraffin embedded human breast cancer cell line xenografts

Cell Line β-actin MT1-MMP MMP-1 MMP-3
MCF-7 Tumour 2+ Tumour 1+ Tumour 1+ Tumour 1+
  Stroma 1+ Stroma 1+ Stroma 1+ Stroma 1+
MDA-MB-231 Tumour 2+ Tumour 3+ Tumour 0+ Tumour 1+
Spleen Stroma 2+ Stroma 0+ Stroma 0+ Stroma 0+
MDA-MB-231 Tumour 2+ Tumour 2+ Tumour 2+ Tumour 1+
Mesenteric Stroma 2+ Stroma 1+ Stroma 2+ Stroma 1+
MDA-MB-435 Tumour 2+ Tumour 2+ Tumour 2+ Tumour 3+
  Stroma 2+ Stroma 0+ Stroma 0+ Stroma 0+
Hs578T Tumour 1+ Tumour 1+ Tumour 1+ Tumour 1+
  Stroma 1+ Stroma 1+ Stroma 0+ Stroma 2+