Table 4 Association between XRCC1 condon 194 and 399 polymorphisms and NPC risk stratified by smoking status
From: Polymorphisms of XRCC1 genes and risk of nasopharyngeal carcinoma in the Cantonese population
Genotype | Non smoking | Smoking | ||||||
|---|---|---|---|---|---|---|---|---|
| Â | Cases | Controls | Adjusted ORa (95%CI) | P value | Cases | Controls | Adjusted ORa (95%CI) | P value |
XRCC1 Arg194Trp | ||||||||
   Arg/Arg | 78 | 157 | 1.00 |  | 154 | 78 | 1.00 |  |
   Arg/Trp | 58 | 155 | 0.73(0.48–1.11) | 0.14 | 108 | 62 | 0.87(0.57–1.33) | 0.52 |
   Trp/Trp | 10 | 29 | 0.77(0.35–1.70) | 0.52 | 9 | 14 | 0.34(0.14–0.82) | 0.017* |
XRCC1 Arg399Gln | ||||||||
   Arg/Arg | 85 | 185 | 1.00 |  | 156 | 85 | 1.00 |  |
   Arg/Gln | 50 | 140 | 0.73(0.47–1.12) | 0.14 | 102 | 60 | 0.90(0.59–1.38) | 0.62 |
   Gln/Gln | 11 | 18 | 1.42(0.63–3.23) | 0.40 | 21 | 12 | 0.91(0.41–1.99) | 0.81 |