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Table 4 Metastasis: incidence in preoperative versus postoperative irradiation group

From: High incidence of metastatic disease in primary high grade and large extremity soft tissue sarcomas treated without chemotherapy

 

metastasis

radiotherapy

No

yes

postoperative

17 (51.5%)

16 (48.5%)

preoperative

1 (12.5%)

7 (87.5%)

total

18 (43.9%)

23 (56.1%)

  1. Metastatic disease was more likely to occur (p = 0.046) in the preoperative radiation therapy group. Most of the metastases (83%) occurred in multiple localisations almost simultaneously (n = 11) or in the lung (n = 8). Three times metastasis to lymph nodes (13%) and once to bone (4%) was noted.