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Table 4 Metastasis: incidence in preoperative versus postoperative irradiation group

From: High incidence of metastatic disease in primary high grade and large extremity soft tissue sarcomas treated without chemotherapy

  metastasis
radiotherapy No yes
postoperative 17 (51.5%) 16 (48.5%)
preoperative 1 (12.5%) 7 (87.5%)
total 18 (43.9%) 23 (56.1%)
  1. Metastatic disease was more likely to occur (p = 0.046) in the preoperative radiation therapy group. Most of the metastases (83%) occurred in multiple localisations almost simultaneously (n = 11) or in the lung (n = 8). Three times metastasis to lymph nodes (13%) and once to bone (4%) was noted.