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Table 4 Haplotype analysis of intragenic BRCA2 polymorphisms associated with the 9106C>T BRCA2 mutation.
| Polymorphisms | Family 25 | Isolated cases | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Position | Nucleotide change | BR22 | BR23 | BR99 | BR100 | BR101 | BR102 | BR103 | BR175 | BR342 | TBL 38 |
| M | w.t. | w.t. | M | M | M | w.t. | M | M | M | ||
| EX2 | 203G>A | G>A | G-G | G>A | A-A | A-A | A-A | G-G | G>A | G>A | G>A |
| INTR8 | IVS8+56C>T | C-C | C-C | C>T | C>T | C-C | C-C | C-C | C>T | C-C | C>T |
| EX10B | 1342A>C | A>C | C-C | A-A | A-A | A-A | A-A | C-C | A-A | A-A | A-A |
| EX11-J | 3624A>G | A>G | A-A | A>G | G-G | G-G | G-G | A-A | A>G | A>G | A>G |
| EX11K | 4035T>C | T-T | T-T | T>C | T-T | T-T | T-T | T-T | T-T | T>C | T-T |
| INTR11Q | IVS11+80del4 | -4/4 | 4/4 | -4/4 | -4/-4 | -4/4 | -4/-4 | 4/4 | -4/4 | -4/4 | -4/4 |
| EX14A | 7470A>G | A>G | A-A | A>G | G-G | G-G | G-G | A-A | A>G | A>G | A>G |
| INTR17 | IVS16-14T>C | T>C | T>C | T>C | C-C | C-C | C-C | T>C | C-C | T>C | T>C |
