Prominent mobility change of Hic-5 in GSAO-treated PWBC in low and high serum culture. Cells were treated with GSCA or GSAO as indicated for 24 h and analysed for Hic-5 expression and mobility. A Comparisonof effects induced by 15 μM GSAO under low and high serumculture conditions. In both cases a prominent band shift of Hic-5 isobserved. B GSAO dose – response of Hic-5 in PWBC culturedin 100% donor serum. A partial mobility shift is observable at 5 μM GSAO, but the band shift is more pronounced at 15 μM GSAO.