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Figure 3 | BMC Cancer

Figure 3

From: Molecular profiling of signalling proteins for effects induced by the anti-cancer compound GSAO with 400 antibodies

Figure 3

GSAO effects Erk, but not p90Rsk or Jnk phosphorylation in PWBC high serum culture. PWBC were cultured in 100% donor serum and treated with GSAO or GSCA for 24 h as indicated.A Phosphorylation of Erk2 on the Thr202/Tyr204 epitope is visible at 50 μM GSAO (upper panel). Total Erk protein levels remain unchanged after GSAO treatment for 24 h (lower panel). B Phosphorylation of Ser380 on p90Rsk is marginally increased at best in high serum cultured PWBC. C Phosphorylation of the Thr183/Tyr185 epitope on Jnks is marginally increased at best in high serum cultured PWBC.

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BMC Cancer

ISSN: 1471-2407

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